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Micro and Nanofluidics

Our research focuses on the development of microfabricated instrumentation and application in various chemical and biochemical problems.



Microfluidics

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High-Efficiency Electrophoretic Analysis of N-Glycans.

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N-Glycan profiles of glycoproteins derived from human serum analyzed by microfluidic capillary electrophoresis (CE) and capillary electrophoresis-electrospray ionization-mass spectrometry (CE-MS).


Nanopores

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Design and characterization of in-plane and out-of-plane nanofluidic devices.

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An SEM image (left) and AFM image (right) of a 20° tapered nanofunnel formed by electron beam lithography.


Bacteria

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Programmable, pneumatically actuated microfluidic device with an integrated nanochannel array to track development of individual bacteria.

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Tracking of live cells by video microscopy.


Sensing

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Characterize the assembly of hepatitis B virus core protein dimers into T = 3 and T = 4 icosahedral capsid by resistive-pulse sensing.

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Improve the practical-size resolution by multicycle resistive-pulse sensing with four pores in series.


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